BDBM259879 US10308662, Compound 118::US9505780, 118

SMILES ONC(=O)c1ccc(cc1)-c1csc2c1oc(cc2=O)N1CCOCC1

InChI Key InChIKey=SEKOPSVILCFYRX-UHFFFAOYSA-N

Data  10 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 259879   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Signal Rx Pharmaceuticals

US Patent
LigandPNGBDBM259879(US10308662, Compound 118 | US9505780, 118)
Affinity DataIC50:  90nMAssay Description:Several TP Scaffold compounds were tested for inhibition activity against isoforms of PI3K (alpha, beta, gamma, and delta isoforms) and the bromodoma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent